منابع مشابه
Genome Maps, a new generation genome browser
Genome browsers have gained importance as more genomes and related genomic information become available. However, the increase of information brought about by new generation sequencing technologies is, at the same time, causing a subtle but continuous decrease in the efficiency of conventional genome browsers. Here, we present Genome Maps, a genome browser that implements an innovative model of...
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The human genome is a mosaic of isochores, which are long DNA segments (z.Gt;300 kbp) relatively homogeneous in G+C. Human isochores were first identified by density-gradient ultracentrifugation of bulk DNA, and differ in important features, e.g. genes are found predominantly in the GC-richest isochores. Here, we use a reliable segmentation method to partition the longest contigs in the human g...
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The Genome-Linked Application for Metabolic Maps (GLAMM) is a unified web interface for visualizing metabolic networks, reconstructing metabolic networks from annotated genome data, visualizing experimental data in the context of metabolic networks and investigating the construction of novel, transgenic pathways. This simple, user-friendly interface is tightly integrated with the comparative ge...
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De Bruijn graphs provide a framework for genome assembly, where the correct reconstruction of the genome is given by one of the many Eulerian tours through the graph. The assembly problem is complicated by genomic repeats, which allow for many possible Eulerian tours, thereby increasing the de Bruijn graph complexity. Optical maps provide an ordered listing of restriction fragment sizes for a g...
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ژورنال
عنوان ژورنال: Science
سال: 1991
ISSN: 0036-8075,1095-9203
DOI: 10.1126/science.1925580